what's a normal ASO titer?

[MedicinePowder]

on the nmbe assessment exam, I had a question about a guy with a nephritis and a ASO titer of 1:100. i was stuck between IgA nephritis and post-strep, since i could not remember what ASO titer was normal/abnormal.

anyone?

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[daisygirl]

According to medline the normal value is-
The ASO level is usually less than 160 Todd units per milliliter.

I looked in my lange micro/immuno text and normal, or abnormal, values were not given. Why do I have a feeling that this question came from the second assessment? This reminds me that I need to study

 

[Resident Alien]

I would think you shouldnt have a positive ASO titer (since it stands for anti streptolysin O) if youve not had a case of Strep pharyngitis or impetigo, atleast for exam puposes 😀 . Anyone else agree?

 

[scully]

absolutely

 

[bigfrank]

These are the types of questions that you do NOT need to worry about on the exam. If the ASO is positive, look for sequelae of GAS.

Don't get hung up on these nitpicky details. 90+% of the exam is applying concepts.

 

[daisygirl]

I would think you shouldnt have a positive ASO titer (since it stands for anti streptolysin O) if youve not had a case of Strep pharyngitis or impetigo, atleast for exam puposes 😀 . Anyone else agree?

This is the link where I got the info from:

http://www.nlm.nih.gov/medlineplus/ency/article/003522.htm

 

[MedicinePowder]

thanks to everyone for adding their input. in terms of not worrying about this type of question, it was a question from the second assessment so i figured it would be good to clear it up.

also, one can have a given ASO titer and be uninfected because there's a reference range for ASO titer, as Daisy noted. i'm thinking the 160 todd/ml may be translated to 1:160 and therefore someone with a 1:100 would be normal?

 

[barone ROCKS]

kaplan says >200 is significant

 

[Gauss]

that's a lousy question
Usually patient presents for treatment of strepthroat and receives anitbiotics which throws the whole ASO titer way off. Acute Rheumatic Fever and Post Strep GlomNeph have variable titers which can overlap.
Generally in ID titres around 1:32 or higher are considered positive, sometimes 1:16. Anything low 1:1, 1:2 are negative.

 

[ahmed500]

It is possible to explain that the antibody (antibodies ASO) which is formed in the body may remain in the body and blood for a long time and may be up to several months after the injury of the person, that is, There may be someone who has been infected with strept. Group A and after treatment, after two or three months, he performed an analysis (ASO) and found that it is high. We conclude that it is not possible to diagnose the disease with this analysis only, but some other analysis Accompanying him in addition to the symptoms that appear on the injured.

Causes of elevated ASO levels in the blood are the causes of elevated ASO levels in the blood. These include: an inflammation called acute heart disease caused by streptococcus. Other causes include renal ulcer infections due to sepsis in the streptococcus, where the level is between (500 - 5000). The occurrence of parasitic neuropsychological disorders associated with streptococcus. Other causes of reactive arthritis. The occurrence of so-called rheumatic fever (rheumatic fever). Infection with nodal infestations occurs where the level is moderately high.