Where can I find references for intra-drug class differences?

[andy1010]

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As title.
For example differences between ACEI in managing hypertension
thanks in advance!

 

[ravingrabbid]

it's on pharmacist's letter

 

[hereticmnk]

Best resource ever- UpToDate (you probably wont have access to it tho).
Pharmacist letter is decent too I guess
I just looked at therapeutics notes or guidelines from the source (like ADA guidelines for DM).

 

[Ackj]

Best resource ever- UpToDate (you probably wont have access to it tho).
Pharmacist letter is decent too I guess
I just looked at therapeutics notes or guidelines from the source (like ADA guidelines for DM).

What school doesn't give it's students UpToDate access? Pharmacists always ask me to look stuff up for them in sites where they don't have institutional access. That said, I've never looked up drug class overview/comparisons on there, and have usually used Pharmacist's Letter for that purpose. What do you search? I just typed in ACE Inhibitor and got a bunch of articles about disease states where you would use one.

I also thought most class differences were kind of based off of what drug was used in what trial, ie just because enalapril reduced mortality in CONSENSUS, doesn't mean that lisinopril or ramipril would not similarly reduce mortality. I usually use class comparisons for formulary dose equivalence than indications though.

 

[owlegrad]

PL FTW, no question. I use it multiple times per day without a doubt, mostly to check equivalent doses, but also to find out what they recommend as a substitution. For example I very recently went on there to check what they recommend in place of Bystolic and I was VERY pleased with what I found. 👍

And all I had to do was run a search for 'Bystolic' to find it!

 

[hereticmnk]

What school doesn't give it's students UpToDate access? Pharmacists always ask me to look stuff up for them in sites where they don't have institutional access. That said, I've never looked up drug class overview/comparisons on there, and have usually used Pharmacist's Letter for that purpose. What do you search? I just typed in ACE Inhibitor and got a bunch of articles about disease states where you would use one.

I also thought most class differences were kind of based off of what drug was used in what trial, ie just because enalapril reduced mortality in CONSENSUS, doesn't mean that lisinopril or ramipril would not similarly reduce mortality. I usually use class comparisons for formulary dose equivalence than indications though.

My school didn't have access to UpToDate . I had it on my clinical rotations however. It is srsly the best resource I have used. It gives you a dz based approach to drugs. Like for example, HF will list all the ACEi that have clinical evidence for HF, which is brilliant.

If you are just interested in different classes of drugs, then a pharmacological textbook would be better than Pharmacist letter.

 

[andy1010]

my institution got uptodate subscription but not PL...uptodate seems doesnt have any comparison between intra-class...
where can i find one for free? coz i am out of state..seems hard to pay even if i want to...

 

[hereticmnk]

my institution got uptodate subscription but not PL...uptodate seems doesnt have any comparison between intra-class...
where can i find one for free? coz i am out of state..seems hard to pay even if i want to...

A PubMed search might lead to some review articles. What exactly are you looking for 😕
Can you be more specific?