Where in the cell stuff takes place

[Melomare17]

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Can someone post a quick overview of where in the cell each cycle takes place

like where does glycolysis happen, citric acid cycle, fatty acid oxidation, oxidative phosphorylation, etc.

 

[pfaction]

Glycolysis: Cytoplasm
Everything else: Mitochondria matrix
ATP synthesis: Mito Inner Membrane

 

[SaintJude]

Glycolysis & Fermentation : Cytoplasm

Fatty acid activation (synthesis) : cytoplasm

Beta oxidation of fatty acid (leading to production of Acetyl CoA) : mitochondrial matrix

Pyruvate decarboxylation (Pyruvate--> Acetyl CoA): mitochondrial matrix

Citric Acid Cycle: Mitochondrial Matrix

Electron Transport Chain/ATP synthesis : Inner mitochondrial membrane

Deamination of Amino Acids (Breakdown of Amino Acids) : in humans, mostly in individual cells of liver
Byproduct is Ammonia and urea (just got it wrong on a question)

Ah, well pfaction covered most of it already

 

[HollowSuperet36]

Dumb question since it was on an mcat. Both pro and euk carry out ATP production via ATP synthase where is this respectively?

 

[pfaction]

Eukaryote: Mito Inner Membrane
Prokaryote: Membrane

Remember; mitochondria are like gram negative bacteria. They have an inner membrane and an outer membrane, so their ATP synthase is in the inner membrane, pumping into the intermembrane space. this is analogous to the periplasmic space iirc.

 

[Melomare17]

wow thanks for that! i kept getting confused based off how it was worded.

 

[SaintJude]

Eukaryote: Mito Inner Membrane
Prokaryote: Membrane

Remember; mitochondria are like gram negative bacteria. They have an inner membrane and an outer membrane, so their ATP synthase is in the inner membrane, pumping into the intermembrane space. this is analogous to the periplasmic space iirc.

Ah good point.

 

[MedPR]

Also, in relation to TCA and ETC, the intermembrane space is more acidic than the matrix.

 

[Class1P]

just think of a Mitochondria as a symbiotic bacteria... which (most theories believe) that it is.

 

[hellocubed]

ATP synthesis is also carried out in the cytoplasm (glycolysis).

It's the majority of ATP synthesis that is carried out in the membrane/mitochondria