Why does Aripiprazole end in 'zole' if its not a PPI?

[ebrown1985]

I'd imagine this is can be a bit confusing to students learning drug classes, so I was just wondering.

Also, the Saturday Night Live sketch advertises Abilify (with close to the same generic name 'arirazole') for people with dementia, when in reality it's contraindicated for such patients:

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[ActinicKeratosis]

Ketaconazole also ends in "zole" and is not a PPI. I think there are plenty of examples in pharmacology that don't obey general naming rules.

 

[Stagg737]

Probably has to do with their chemical make-up. Azoles have rings with nitrogen in them, so do all the '-piprazoles' along with the '-azole' anti-fungals as far as I know.

 

[Hangry]

I'd imagine this is can be a bit confusing to students learning drug classes, so I was just wondering.

Also, the Saturday Night Live sketch advertises Abilify (with close to the same generic name 'arirazole') for people with dementia, when in reality it's contraindicated for such patients:

Abilify is aripiprazole. And did you really expect an snl skit to be medically accurate??

 

[Taddy Mason]

According to the pharmacist (who has been in practice for almost 40 years and been very active in teaching, research, and national pharm organizations) that gave 99% of the pharm lectures at my school, there has been more than one push to standardize generic drug names over the years. However, due to differing opinions amongst people in the industry (e.g., pharmacologists and pharm chemists, marketing people, and those in actual practice/clinical pharmacists and physicians) the results haven't been perfect.

 

[Psai]

Man and people be like hey we need to cut out organic chemistry

 

[sliceofbread136]

It is a bit weird since it doesnt have an azole group, where as something like ketoconazole or omeprazole does.

Maybe I'm missing something since I forgot all of ochem

 

[GoljansRightBicep]

And did you really expect an snl skit to be medically accurate??

Well where else to you expect us to learn about medicine? Cracking open a book was so last decade...

 

[ebrown1985]

Thanks for all the responses. I actually completely forgot about the antifungals. I guess a standardization of drug names could potentially lead to mass chaos in the pharmaceutical community.

Well where else to you expect us to learn about medicine? Cracking open a book was so last decade...

I actually get all my medicine from House MD. 😉