From what I've heard is that to an extent..yes, you can, but the caveat being..where have you been working since then? If you've been working at Walgreen's, your clinical skills may be getting rusty. Retail pharmacists have a totally different skill set of being able to field all kinds questions and multitasking. I think I have heard pharmacists on this board saying that 3 years is probably the absolute cap of being able to go back and do a residency. Also, as a resident, you'd be making only about 1/3 to 1/2 the amount you had been previously making, so it's harder to go back. Also harder to get back into a school mindset, because as a resident, they'll have you doing a bunch of projects in addition to your work hours..