beta oxidation unsaturated fatty acid (cis between C2 and C3)

[kevv]

As I know, in oxidation of unsaturated fatty acid, cis or trans double bond between C3 and C4 are transformed into a trans double bond between C2 and C3 (i.e. between alpha and beta carbon atoms) by enol-CoA isomerase
So, all cis (C2n+1=C2n+2) and trans (C2n+1=C2n+2) have no problem, n=1,2,3...

For cis double bond between C4 and C5, the fatty acid undergoes the first step of beta oxidation, so then it has cis (C4=C5) and trans (C2-C3), and the double pairs will be transformed into trans (C3=C4) by dienoyl CoA reductase. Trans (C3=C4) will become trans (C2=C3) as stated in the first paragraph
So, all cis (C2n+2=C2n+3) have no problem in oxidation

for trans (C2n=C2n+1), there is no problem, because trans C2 and C3 is formed in the first step of beta oxidation and every cycle of beta oxidation removes two carbon (alpha and beta) from the chain

Then, what about cis (C2=C3)?

Thank you!!

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[andelJ94]

bamp