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Accoridng to Uworld (q 688) one toxicity is that it causes pulmonary edema - it draws too much fluid into vasculature -> higher hydrostatic pressure -> pulmonary edema. Okay I can believe that
It also says mannitol drawing water out of cells will also pull potassium out causing hyperkalemia and metabolic acidosis.
Questions:
Why does mannitol pulling water out also cause K+ to come out? Is it just because there is less water in the cell so K+ comes out to keep the normal K+ amt in a cell?
Why does that cause metabolic acidosis? Wouldn't K+ coming out will cause H+ to go into a cell and thus cause alkalosis?
Thanks
It also says mannitol drawing water out of cells will also pull potassium out causing hyperkalemia and metabolic acidosis.
Questions:
Why does mannitol pulling water out also cause K+ to come out? Is it just because there is less water in the cell so K+ comes out to keep the normal K+ amt in a cell?
Why does that cause metabolic acidosis? Wouldn't K+ coming out will cause H+ to go into a cell and thus cause alkalosis?
Thanks