^^ what he said. I would still send some DO apps out and see what happens if you have the money for it. In the meantime, I would look into the SMPs you referred to, but also still retake some of the core classes you got Cs in. Yes, total grade replacement is out of the window now, but retaking those classes at a CC will still go a long way towards removing some of the red flags from your app. Especially the C- in bio 2, I believe some schools require a C in all pre reqs.
Either way, you still have a good shot. No one really knows how this is going to effect things. If you want this bad enough you can still achieve it.
Good luck!