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Would you treat the flair (edema?)
Volumes for Low grade Glioma in the supratentorium
- Thread starter radonc22
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Maybe, need more information on the specific clinical scenario. Is this post-op after STR? GTR? Biopsy?
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What would you do for recurrent disease status post STR with fractionated therapy.
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If this is recurrent disease, it could have undergone malignant transformation to WHO III/IV. Has the recurrence been biopsied? Is there enhancement?
Regardless, chemo is standard of care for recurrent LGG s/p XRT per NCCN guidelines. Especially if the patient hasn't seen chemo before, I would do chemo with temozolomide first (or PCV I suppose, if you are a masochist), and save reirradiation for if the patient progresses on chemo. Whether and which component of FLAIR to include is complex for recurrent disease, and would depend on the original treatment fields, location of recurrence, etc.
Regardless, chemo is standard of care for recurrent LGG s/p XRT per NCCN guidelines. Especially if the patient hasn't seen chemo before, I would do chemo with temozolomide first (or PCV I suppose, if you are a masochist), and save reirradiation for if the patient progresses on chemo. Whether and which component of FLAIR to include is complex for recurrent disease, and would depend on the original treatment fields, location of recurrence, etc.
