High Yield Molecular bio question

sorry

Jonathan13180 said:

Why is the 1999 edition selling for upwards of $500? Can anyone tell me why and how it is that much better than the current one?

Thanks

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I think it's said to be better since it's a more concise version of what you need to know versus the current editions with far too much in it. That said, I've never looked at either but that's what I read from SDN.

while all the M2s were busy picking up pharm recall in August from our yearly booksale, I picked up 1999 Cell bio for $5

Thanks sdn!

Now I can reimburse myself the USMLE registration $$$

i havent read mine yet and i have an unopened copy of it. maybe thats why i failed step1. help guys any advice? i dont know why i did, i was getting high 50's low 60's on usmleworld. need your input please.

I have two friends who just took the boards and did very very well. They both said this book helped them tremendously. I asked them for it, but they said they are keeping it because it is an excellent reference for the less molecular inclined. It is a hidden gem. I been looking for one but it is selling for 100 or 150 on amazon. Damn.

The new one stresses people out--too much unnecessary info and just trying to sift through it to find the relevant info is painful.

Jonathan13180 said:

Why is the 1999 edition selling for upwards of $500? Can anyone tell me why and how it is that much better than the current one?

Thanks

Click to expand...

estrogenic said:

i havent read mine yet and i have an unopened copy of it. maybe thats why i failed step1. help guys any advice? i dont know why i did, i was getting high 50's low 60's on usmleworld. need your input please.

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in order to get advice, you are gonna have to give more info about how you prepared for Step 1. what resources did you use? how long did you study for? etc

lankysudanese said:

in order to get advice, you are gonna have to give more info about how you prepared for Step 1. what resources did you use? how long did you study for? etc

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hi, i took the kaplan retreat. did usmleworld and was getting high 50's low 60's and some 70's tutor mode but i still timed it. didnt read first aid. HELP!!!!!! I AM SO DISCOURAGED

So the 1999 edition of HY Cell and Mol Bio is selling for $399. 🙄
For those of us who can't afford to buy too many $400 dollar books, do you think it's still worth getting the current edition of HY Cell?

I didn't think Cell/Mol Bio would be very high-yield on the Boards, but I'm noticing that it's my weakest area on the QBank, so it might be good to review.

funshine said:

I didn't think Cell/Mol Bio would be very high-yield on the Boards, but I'm noticing that it's my weakest area on the QBank

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I agree. Cell/mol bio was my weakest area in Qbank (~70%) but was never highly tested in either the NBMEs or the real test. It's a great strategy to work on your weak points, but I don't think that spending $300+ and countless hours trying to get this specific copy of HY is a good idea. You can get a good review of mol bio just by looking through your MS1 notes.

Would the Kaplan Biochemistry book be good enough if we couldn't get this (perhaps overrated) HY book?

Knicks said:

Would the Kaplan Biochemistry book be good enough if we couldn't get this (perhaps overrated) HY book?

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Kaplan biochem is excellent

Knicks said:

Would the Kaplan Biochemistry book be good enough if we couldn't get this (perhaps overrated) HY book?

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There is quite a difference between biochemistry and molecular biology. Also, I don't think the hy book is overrated it just cost tabookuuu money, but is an excellent book.

^^^^^ Thanx for those last 3 responses.


Does Kaplan cover Molecular Biology at all anywhere in there books?

wow i bought this book a 3 months ago for $8... good to see my neuroticism payed off...

SeventhSon said:

wow i bought this book a 3 months ago for $8... good to see my neuroticism payed off...

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Hehe...me too. I have to say thanks to Dr. Bagel for pointing out the price surge on Amazon while you could still get them at half.com for $10!

Knicks said:

^^^^^ Thanx for those last 3 responses.


Does Kaplan cover Molecular Biology at all anywhere in there books?

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Yes, it does. Kaplan lecture note "biochemistry" consists of molecular biology, biochemistry, and genetics !

GL

Ragnarok said:

Yes, it does. Kaplan lecture note "biochemistry" consists of molecular biology, biochemistry, and genetics !

GL

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Would you by any chance know if the Kaplan biochem "molecular" section is better than the HY molecular book? I have both and not sure which one is better to use.

Thanks!

beponychick said:

Would you by any chance know if the Kaplan biochem "molecular" section is better than the HY molecular book? I have both and not sure which one is better to use.

Thanks!

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I have both, and I'm using kaplan...it does a beautiful job of integrating everything together...genetics, cell bio, molecular & biochem!

DO it right said:

I have both, and I'm using kaplan...it does a beautiful job of integrating everything together...genetics, cell bio, molecular & biochem!

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I agree.
I also have both and prefer Kaplan. The molecular section in Kaplan biochemistry is much more comprehensive and detailed, but still easy to get through. IMO

funshine said:

So the 1999 edition of HY Cell and Mol Bio is selling for $399. 🙄
For those of us who can't afford to buy too many $400 dollar books, do you think it's still worth getting the current edition of HY Cell?

I didn't think Cell/Mol Bio would be very high-yield on the Boards, but I'm noticing that it's my weakest area on the QBank, so it might be good to review.

Click to expand...

Are you guys kidding me! Wow. I'm so glad I still have mine.

The question is how long should I hold on to it before I sell, sell, sell!

i really doubt anyone will actually pay that price for a little **** book like that. Geez just buy the new version for like 20 bucks and read the damn thing.no biggie. If anyone does pay 400 for that book, i must say that they are huge idiots.

eur said:

i really doubt anyone will actually pay that price for a little **** book like that. Geez just buy the new version for like 20 bucks and read the damn thing.no biggie. If anyone does pay 400 for that book, i must say that they are huge idiots.

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I completely endorse this statement. 👍

Soon this book will be missing from all library shelves just like the STARS Path by Goljan

I should've bought two.
🙄

OK, so maybe I am out of the loop on this one, but why is the 1999 edition so much better than the 2006? It is the same author I believe and I doubt that it has secret facts in it that were deemed critical to national security and removed.

simpy2000 said:

OK, so maybe I am out of the loop on this one, but why is the 1999 edition so much better than the 2006? It is the same author I believe and I doubt that it has secret facts in it that were deemed critical to national security and removed.

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The 1999 edition is a quick read, and really distills the subject down to the facts you want to know for Step I.

2006 is massive and the additions did not seem to include useful material.

Hence, although the 1999 edition is more convenient, there's no reason to pay lots of money for it -- the new edition and a highlighter should be fine.

lord_jeebus said:

The 1999 edition is a quick read, and really distills the subject down to the facts you want to know for Step I.

2006 is massive and the additions did not seem to include useful material.

Hence, although the 1999 edition is more convenient, there's no reason to pay lots of money for it -- the new edition and a highlighter should be fine.

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I agree with Jeebus on this one. Based on info I got on here and from upperclassman, it would be foolish not to use this book as part of your review for Step 1. With that said, it would be even MORE foolish to pay up to $400-500 dollars for this book. Here is the table of contents for the 1st edition. Just buy the 2nd edition, which you can find anywhere online for a fair price, and just go over the pertinent sections.

High Yield Cell and Molecular Biology by Dudek, 1st edition (1999) – 128 pages (whereas the 2nd edition is 254 pages)
Table of Contents

1. Packaging of Chromosomal DNA
I. Nucleic acids
II. The human genome
III. Chromosome
IV. Genes
V. Chromatin

2. Chromosome Replication and DNA Synthesis
I. Introduction
II. Replication fork
III. Telomere
IV. Damage and repair of DNA
V. Clinical importance of DNA repair mechanism

3. Genetic Recombination
I. Introduction
II. General recombination
III. Site-specific recombination

4. Transposable Elements
I. Introduction
II. Mechanisms of transposition
III. Transposable elements and genetic variability

5. Gene Amplification
I. Introduction
II. Clinical considerations

6. Recombinant DNA Technology
I. Introduction
II. Restriction enzymes
III. Gel electrophoresis
IV. Enzymatic method of DNA sequencing
V. Southern blotting and prenatal testing for sickle cell anemia
VI. Isolating a human gene with DNA cloning
VII. Polymerase chain reaction (PCR)
VIII. Producing a protein from a cloned gene
IX. Site-directed mutagenesis and transgenic animals

7. Control of Gene Expression
I. Introduction
II. Mechanism of gene regulation
III. Structure of transcription factors and gene regulatory proteins
IV. Clinical consideration: growth hormone deficiency and Pit-1 transcription factor
V. The lac operon
VI. Summary

8. Protein Synthesis
I. Transcription
II. Converting an RNA transcript to mRNA
III. Translation
IV. Clinical considerations

9. The Nucleolus
I. Organization of the nucleolus
II. Assembly of the ribosome
III. Ultrastructure of the nucleolus

10. Mutations of the DNA Sequence
I. Silent mutations
II. Missense mutations
III. Nonsense mutations
IV. Frameshift mutations
V. Translocation mutations
VI. RNA splicing mutations
VII. Transposable element mutations
VIII. Trinucleotide repeat mutations

11. Molecular Genetics
I. Polymorphisms
II. Linkage (coinheritance)
III. Population genetics

12. Inherited Diseases
I. Autosomal dominant inheritance
II. Autosomal recessive inheritance
III. X-linked recessive inheritance
IV. Mitochondrial inheritance
V. Multifactorial inheritance
VI. Table of inherited disorders

13. Multifactorial Inherited Diseases
I. Definition
II. Example: type 1 diabetes

14. Proto-oncogenes, Oncogenes, and Anti-oncogenes
I. Definitions
II. Designations
III. Classification of oncogenes
IV. Mechanism of action of the ras proto-oncogene
V. Anti-oncogenes (tumor-suppressor genes)
VI. Molecular pathology of colorectal cancer

15. The Cell Cycle
I. Phases of the cell cycle
II. Control of the cell cycle
III. Stages of the M phase

16. Homeotic Genes and Anterior-Posterior Body Pattern Formation
I. Introduction
II. Human homeotic genes

17. Mitochondrial Genes
I. Introduction
II. Gene products that are encoded by mitochondrial DNA (mtDNA)
III. Other mitochondrial proteins
IV. Mitochondrial diseases

18. Molecular Immunology
I. The clonal selection theory
II. The B lymphocyte (B cell)
III. The T lymphocyte (T cell)
IV. Clinical considerations

19. Receptors and Signal Transduction
I. Ion channel-linked receptors
II. G-protein-linked receptors
III. Enzyme-linked receptors
IV. Steroid hormone (intracellular) receptors
V. Receptor types
VI. Nitric oxide (NO)
VII. Receptor-mediated endocytosis

i just cracked my copy open - the book only has 99 pages. that is, unless the person i just bought it from tore out 29 of them.

there is an auction on ebay right now that has a whole stack of HY books (and includes 99 CMB). here is the link:
http://cgi.ebay.com/ws/eBayISAPI.dl...59871&_trksid=p3907.m32&_trkparms=tab=Bidding

note: this is not my auction, i just tried to buy it cheap so i could get in on the $400 frenzy on half.com.

Gozar said:

i just cracked my copy open - the book only has 99 pages. that is, unless the person i just bought it from tore out 29 of them.

there is an auction on ebay right now that has a whole stack of HY books (and includes 99 CMB). here is the link:
http://cgi.ebay.com/ws/eBayISAPI.dl...59871&_trksid=p3907.m32&_trkparms=tab=Bidding

note: this is not my auction, i just tried to buy it cheap so i could get in on the $400 frenzy on half.com.

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It's 128 pgs.

I'm in the process of figuring out my booklist for step 1 this summer, and I was wondering if anyone found it necessary to use the HY (1999) AND Kaplan Biochem to supplement FA?

Basically, if i use HY and FA, should that cover me on biochem?

Can anyone tell me wheather this older version of high yield are also better for other subjects? I was looking through first aid and they seem to recomend the newer versions but i only have the older ones which actually seem to be all less pages, anyone