7 HY HIV qs *

[shigella123]

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Correct answers for these?

1. If the mother is HIV-Positive, The Chance (%) of Children to have the positive test at birth is :
A. 50%
B. 2-10%
C. 100%
D. 0%

2. Breast-feeding HIV-positive mothers increases transmission rate to _____.
A. 50%
B. 2-10%
C. 100%
D. 0%

3. The best way to protect the infants from an HIV-positive mother by :
A. AZT administration to mother
B. AZT administration to mother and to child after birth
C. C-section, AZD administration to mother , and to child after birth
D. AZT and Nevirapine administration to mother and child

4. What immune cells does the HIV infect?
A. CD4 positive (T –4 lymphocytes)
B. Macrophages
C. Both a and b

5. What is Acute HIV Syndrome?
A. When HIV progresses into AIDS
B. The stage immediately after HIV infection when the patient falls ill
C. The final fatal disease for the AIDS patient
D. None of the above

6. How do health care workers protect themselves from infection?
A. In case of contact, they are advised to take PEP drugs
B. They don’t run a risk of contracting the infection
C. Workers must take all possible precautions including using waterproof gloves, handling needles with care etc
D. Both a and c

7. Which test gives the most accurate confirmation of HIV presence?
A. ELISA Test
B. Western Blot Test
C. Oral Fluid Test
D. All of the above
-----



Two individuals become infected with HIV at approximately the same time. John progresses rapidly to full-blown AIDS and dies within 3 years. Superman is still asymptomatic after 10 years. One possible explanation is that the virus in John is probably expressing a high amount of activity of which regulatory gene product?

A. vif

B. vpr

C. tat

D. env

E. pol



-------------------
Answer: C.

-------------------
Other info:
Homozygous CCR5 mutation ..................>IMMUNE
Heterozygous CCR5 mutation..................>slow course
CXCR1 mutation.....................................>rapid progression to full-blown AIDS

 

[Ionian]

 

[1dayatatime]

weird. i have written down "nef dec's MHC1 on infected cells, enhancing viral replication" -- that seems to imply the opp of what you're saying nef does. wtf?

 

[CherryRedDracul]

1. If the mother is HIV-Positive, The Chance (%) of Children to have the positive test at birth is :
A. 50%
B. 2-10%
C. 100%
D. 0%

This doesn't look correct. Which test are they talking about? ELISA will be near 100% positive because it will detect anti-HIV IgG, but that's why you don't use ELISA in newborns. Rather, you do a PCR HIV test which certainly should not be anywhere around 100% positive.

And as for the breastfeeding question, according to UpToDate, breastfeeding increased the risk of transmission up to 10% over two years. That's a far cry from 50%. http://www.uptodate.com/contents/hiv-and-pregnancy-beyond-the-basics

With regards to the AZT and nevirapine vs. AZT and C-section, I never would have guessed that, especially how close the two percentages seem to be. With that said, according to UpToDate, nevirapine is generally not recommended for women with a CD4 count > 250 because they are at a higher risk of liver failure. I guess is the mother dies from liver failure, the infant is protected from her virus-laden breast milk. Can't feed her infant if she's dead, nom sayin'?

weird. i have written down "nef dec's MHC1 on infected cells, enhancing viral replication" -- that seems to imply the opp of what you're saying nef does. wtf?

That's what I thought. If those questions are from the Kaplan lecture notes, I'd ditch them fast and stick to any of Fadem's review books instead.

 

[shigella123]

I'm glad I shared these because these qs are posted on other forums by other students with the wrong info and I would have learned the wrong info too. Thanks a lot CRD for the correct info!

 

[1dayatatime]

CherryRedDracula - you are so helpful! In this and in other posts I've posted/seen. Thanks! But what do you mean Fadem's books (on HIV?) She has only behavioral stats as far as I know. And they don't say too much about HIV (I have BRS).

 

[CherryRedDracul]

CherryRedDracula - you are so helpful! In this and in other posts I've posted/seen. Thanks! But what do you mean Fadem's books (on HIV?) She has only behavioral stats as far as I know. And they don't say too much about HIV (I have BRS).

For behavioral science in general, Dr. Fadem is top-notch IMO, considering she personally taught our school's behavioral classes and she does a killer job teaching for both the shelf and the Step exams. I'd call her the Goljan/Sattar of behavioral sciences.

For HIV, I would know about the various viral proteins, receptors they bind, course of infection, which diagnostic tests to use, and especially the drugs and their side effects. Stuff beyond that like in-depth management of HIV, especially in pregnant mothers, seems like stuff for the next few Steps. All I would remember about that is that you give zidovudine to pregnant mothers and newborn infants.

Oh, and know the opportunistic infections cold.