I was told (and did) that you should replace the 3 hr class and 1 hr lab with a 4 hr combined or v/v. They told me that I had to replace the lab as well, but then I know others who have kept the first lab, so it likely depends on who happens to be verifying your transcript.
I was also told that if you took a 4hr class w/o lab for say organic that they would take that in place of a 3hr organic class.
Get everything in early so you have time to make corrections and then it doesn't matter.