Step I Acetaminophen is Cox-2 selective, why give anything else?

[boarding]

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Why would you give non-selectices like naproxen or ibuprofen, if acetaminophen is cox-2 selective and won't damage the gastric epithelium?

Thanks in advance.

 

[thomasce]

no anti-inflammatory affects

 

[animando]

my new way of thinking is rather "no effect at all" http://www.thelancet.com/journals/lancet/article/PIIS0140-6736(14)60805-9/abstract

but yeah acetaminophen doesn't target COX2.

 

[lunalight]

Acetaminophen is COX-3 selective. It inhibits the production of PGs in the CNS which gives it analgesic and antipyretic effects, but no anti-inflammatory or platelet activity.

 

[seminoma]

Lest we forget the increased risk of thrombosis of the cox-2 selectives.