acidosis/alkalosis question

[DancingKoala]

pH = pK + log [HCO3/CO2]

If HCO3 inc, then pH inc = metabolic alkalosis
If HCO3 dec, then pH dec = metabolic acidosis
If CO2 inc, then pH dec = respiratory acidosis
If CO2 dec, then pH inc = respiratory alkalosis


What I don't understand is, how does vomiting promote metabolic alkalosis, and diarrhea/renal failure/salicylate can lead to metabolic acidosis.

How does vomiting increase HCO3?

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[Being human]

during vomitting there is loss of acid and so therefore that would lead to metabolic alkalosis which is compensated to a certain degree by respiratory acidosis..

In diarrhoea there is excessive loss of bicarbonate and potassium from the GI tract leading to metabolic acidosis
In renal failure, since the Dt acts as the buffering unit of the kidney by reabsorbing the bicarbonate there, but since in renal failure it doesnt work it would definitely lead to metabolic acidosis
In salicylate poisoning there is increased intake of acid like aspirin leading to metabolic acidosis..
Hope that helps...gudluck...

 

[Contach]

during vomitting there is loss of acid and so therefore that would lead to metabolic alkalosis which is compensated to a certain degree by respiratory acidosis..

In diarrhoea there is excessive loss of bicarbonate and potassium from the GI tract leading to metabolic acidosis
In renal failure, since the Pt acts as the buffering unit of the kidney by reabsorbing the bicarbonate there, but since in renal failure it doesnt work it would definitely lead to metabolic acidosis
In salicylate poisoning there is increased intake of acid like aspirin leading to metabolic acidosis..
Hope that helps...gudluck...

To add to this....
You can't think of the equilibrium between CO2 and HCO3 when trying to figure out if vomitting causes acidosis or alkalosis because this equilibrium doesn't occur in the stomach. The equillibrium of CO2 and HCO3 occurs in the kidney tubular cells. Instead, what does occur in the stomach glands, is HCl secretion by parietal cells of the stomach. Thus H+ leaves the body when vomiting.