Acute intermittent porphyria

[Ven0m]

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Anyone know if anemia is generally a problem in this disease? It's a defect in porphobilinogen synthase, which is required for heme synthesis (as far as I know). Where would we get the heme from then? Or is the specific isoenzyme mutated not found in RBCs (eg, only found in hepatocytes)?

 

[navigator]

It is not