addiction: choice vs illness

Started by PikminOC
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PikminOC

MD Attending Physician
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This is attributed to James Holmes: but that is not the gist of this conversation. As psychiatrists who treat addiction what do you think about the content?

It was created in March, 2010, and nobody’s logged in since 1/25/11. Username: Jimbo.H. He replied to the article on “New laws expand mental health, addiction treatment” and his comment was posted on Saturday, October 9, 2010:
Actually, addiction IS a “choice.” I don’t know of anyone who is addicted to a substance, be it marijuana, cocaine, alcohol, or cigarettes who didn’t “choose” to pick up a joint, a coke straw, glass of cognac, or light up a cigarette to begin with. We somehow want to sympathize or diminish the fact that addicts in fact DID “choose” to take that first drink, smoke that cigarette, snort that first line, etc. despite the well known risks. We don’t live in 1950s where even doctors smoked and endorsed brands of cigarettes. The dangers of these substances have been known for at least three decades now back to the 1980s, so to say it’s only a “medical” problem and not a “choice” is patronizing at best and insults the intelligence. It seems those who paint addiction/alcoholism as an “illness” or “disease” are more often than not people who are either addicted themselves, were previously addicted, or have a family member or friend with addiction, which, of course, makes it difficult to remain objective and more likely for them to minimize their own or their loved one’s personal responsibility for getting them in that position to begin with. That’s not to say that we shouldn’t provide treatment or coverage for that treatment, but it’s time we stopped making excuses for addictions (being politically correct) and just call a spade a spade.

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We somehow want to sympathize or diminish the fact that addicts in fact DID "choose" to take that first drink, smoke that cigarette, snort that first line, etc. despite the well known risks.

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One of the risks is addiction, and addiction has started to become defined in terms of a disease model. So, while yes, they are often aware of the consequences, the consequence is a disease.

Sex can be the same way. Traveling to Africa is also a risk for contracting a disease. So while it's fairly common knowledge that using a drug can cause desire to use more of a drug which can lead to addiction, I think you can look at other risky behaviors that people weigh the pros and cons of. Some people drive fast, some use guns. Some think that using coke one time won't hurt. Some people think riding a horse won't hurt and can have paralysis, which is treated as a disease. My point is that in all of these cases there is a risk people accept, but I think that the differentiator is that with many drugs there is no possible long-term pay off and the behavior is riskier, so I can understand the stigma.

From my lay perspective, I have heard of two reasons for drugs causing a diseased state of addiction: 1) a suggestion of genetic susceptibility 2) the drugs themselves activate reward centers which then need constant stimulation, which is then inherently described a diseased state.

The other thing about addiction is that it is a disorder that is psychiatric in nature, due to the obsessive need to continue taking drugs in spite of harming the body, just like cutting oneself in spite of the harm. But in the case of someone cutting themselves, which is defined as a disease, there is no known cause. Drug addiction actually has clearer known causes, which I think would make it in some ways more eligible to be elevated to disease status. And while I'm not familiar with anyone saying it, I'm sure some psychiatrists would say drug addiction helps them understand other psychiatric diseases like cutting, in terms of activating that pleasure center.

I've also wondered whether you could argue it's environmental (besides having addicts as parents). For example, dentists have higher rates of drug abuse than other professions, and many suggest it's due to easy access. I doubt many people go into dentistry for drugs, but once it's easily available, it seems to make a difference.

I also don't think you can say that people always know their actions will lead to addictions. Neonates can be born addicted to a variety of drugs, and while I don't want to start an argument, I know that there are patients who are prescribed benzodiazepines without being told about the potential for addiction/tolerance. And then you have to consider that whenever new drugs come out, they are often at first thought not to be addictive (such as benzodiazepines were when first brought to the market, and as were z-drugs, which some doctors are first thought were non-addictive replacements for benzos and even used in the daytime, and later found could be just as difficult to quit). These thoughts are sometimes later disproven.

Also, if it being thought of a disease meant that research were being done into ways to help people withdraw, I think that would be beneficial. My own research has turned up agents like XBD-173, neurontin, l-theanine, suriclone, and others as helping during benzodiazepine withdrawal. None of them is marketed or even researched as potential agents to help with withdrawal, but I identified each as having potentially helpful properties. Unfortunately, it seems like very little if no research is done into that field. If treating it as a disease helped research along, that would be great.

In addition to treating addiction as a disease to help with prevention and treatment, I think it could be helpful in terms of fostering curiosity over the state of the brain even after the addiction has stopped. Going back to benzos since it's what I'm familiar with, brain scans dating back to 1982 showed brain damage in people who took benzodiazepines chronically; however, there hasn't been funding to do MRI studies of benzodiazepine patients, so the topic of brain damage is still unsettled. Some like Professor Heather Ashton think it's a lingering chemical state that causes protracted symptoms, but some scans have found brain shrinkage and other brain damage similar to what alcoholics suffer with.

I think if these are labeled as disease states, they would possibly just from a practical point of view get more attention. I think anything that becomes codified gets more attention and is taking more seriously. My concern with your point is that if you just think of addicts as people who chose a bad way of life and think of the effects of those drugs in a conventional way, you close off the possibility for further interest in developing non-addictive drugs, developing addiction treatment, and understanding long-term physiological changes, which are certainly a disease state, and how those changes should be dealt with.

I think with addiction the most obvious thing to say is how little is known about it and that we should stay open to understanding it. And to me, it seems at least, things don't tend to get cared for or studied unless they are diagnosed and named.

Finally, I don't think the change is to be politically correct. Having a disease doesn't really elevate you to a better place. If you're on a transplant list, having been diagnosed with an addiction is probably a worse disease to have than many others because of the belief that you can't control the disease/addiction.

For me, whether it's a disease or not would only benefit me in terms of potential treatment options as I mentioned. Because I know that in spite of an iatrogenic tolerance to benzodiazepines, the responsibility for withdrawing is completely in my hands. I wouldn't have said that 10 years ago. But now I realize it is reality. There is no one else. If there were a type of proven adjunctive aid, I would use it. And maybe classifying it as a disease state could help with that. But it doesn't change that it is my life and in spite of decisions other people have made, I am the one who will benefit or not depending on far I can get with my withdrawal.
 
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Why can't it be both? Isn't the whole point that the illness impairs your ability to make good choices?
 
If you don't drink alcohol because your father is an alcoholic, doesn't that pretty strongly suggest alcoholism is a disease?

Also, I think that's a bit of an overly cautious approach. I haven't drunk alcohol since I was 9 years old when I had a sip of my parents' campari mixed with orange juice. It was marvelous. What I wouldn't give for a sip of that again! But going on psych drugs at 14, I placed a self-imposed no-drinking-ever rule (along with no lime, grapefruit, or pomegranate) on myself that I've kept to. In my case, I think it's rational, in the case of a child of an alcoholic, I can see why a person would self-monitor and be cautious and why the person might not drink till later in life, especially if he or she is in al-anon as a child, but I think attempting to see if you can drink moderately is reasonable. It doesn't seem as if it's a genetic inevitability that alcoholism is passed on.
 
Your definition of what a "choice" vs. a "disease" isn't precise enough and hence the entire dichotomizing collapses. The reality is that for some people it's a choice, and for some people it isn't, and even for those who meet the conventional definition of addiction, the underlying mechanism is heterogenous.

The reason that the mainstream conceptualization of substance abuse (i.e. NIDA) has evolved today to be at least in large part to be a chronic, relapsing-remitting illness is for several reasons. (1) There is a large body of evidence now that substance abuse and dependence can cause direct, sometimes potentially irreversible changes in the brain that can be detected using even our admittedly crude neuroimaging techniques. (2) Substance abusing patients behave in ways that closely resemble patterns, namely compulsions and impulses, seen in other psychopathologies. (3) There is convincing evidence for a strong genetic component for a number of substance abuse disorders. (4) Several pharmacologic treatments are extraordinarily effective in either reducing use or reducing harm.

Is it true that a proportion of those who abuse drugs can stop voluntarily if they wanted to? Yes. But the fact of the matter is for many substance abusing patients, there is good evidence both from animal models and human experiments that specific circuits in the brain are hijacked in such ways that they are unable to make rational decisions and carry out rational behavior. There is no doubt in my mind (and empirically verified) that methadone saves lives. It's unconscionable and a genuine human rights abuse that in some countries pharmacologic treatment of substance abuse is banned, and that in this country some treatment paradigms preclude the use of pharmacologic agents.


It was created in March, 2010, and nobody's logged in since 1/25/11. Username: Jimbo.H. He replied to the article on "New laws expand mental health, addiction treatment" and his comment was posted on Saturday, October 9, 2010:
Actually, addiction IS a "choice."

:prof:
 
If, for example, you know your dad is an alcoholic, wouldn't the prudent thing to do is abstain at the very least from alcohol?
Sure. And if alcoholism wasn't a disease process that affected decision making regarding substances, that would be easy.
 
One of the recent psych journals is about the link between cannabis and psychosis and the recommended intervention is preventing people who have first degree relatives with psychosis from smoking pot.
 
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Generally the more someone works in the field of addictions, the more they consider addiction as a disease and not a choice. This was validated by a recent research article about Medical Student rotations and opinions after the rotation.

Choice vs Disease... this logic is no different than Diabetes II or Hypertension, someone choosing to eat unhealthily and not exercise.
 
Try doing an eight ball of blow every weekend for a few months, then decide to quit. I'm sure you'll answer your question.
 
I think it's both. I don't like the premise behind AA that they are, "powerless" to control their addiction. Shouldn't the goal be to empower them to control their condition?

I never had my diabetes patients come in multiple times daily for glucose checks and to administer insulin, or to call me to make sure what they plan to eat is appropriate. We provide them the tools, the education, and the support. It's up to them to choose whether or not they want to do it, just as it is up to the addict to choose whether or not he wants to treat his addiction.

If choice was never involved in addiction at all, motivational interviewing would be pointless.
 
I think it's both. I don't like the premise behind AA that they are, "powerless" to control their addiction. Shouldn't the goal be to empower them to control their condition?

I never had my diabetes patients come in multiple times daily for glucose checks and to administer insulin, or to call me to make sure what they plan to eat is appropriate. We provide them the tools, the education, and the support. It's up to them to choose whether or not they want to do it, just as it is up to the addict to choose whether or not he wants to treat his addiction.

If choice was never involved in addiction at all, motivational interviewing would be pointless.

Thanks! This was a very well written post.
 
Try doing an eight ball of blow every weekend for a few months, then decide to quit. I'm sure you'll answer your question.

And then there are those that can take it or leave it. Don't forget that there is a big genetic component at play here also.
 
I think we need to look at the choice or not issue as belonging into a spectrum rather than having a black/white dichotomy. Our actions are at a various levels of internal (or conscious) control, and subject to a number of external influences that sidestep awareness, being genetic or environmental . I think things like substance abuse and food "abuse" clearly have aspects for both, and given the amount of evidence, it's hard to think of either as something majorly determined by our own internal conscious control. I also think it's good to err on the side of doubt for most of the actions we tend to take for granted as being a "choice". A lot of that probably stems from a lack of awareness of the physiologic/psychologic causative agents. And that while admitting that something like free will actually exists; if it does, I think it plays a much, much more limited role than we like to assume.
 
Part of this is also availability. I know it is difficult for some people to believe, but not everyone has easy access to cocaine, marijuana, alcohol (when underage), so people with cormorbid mental illness may not always turn to drugs.