Advantage and Heartgard used together

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Dogtor

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I recently heard a study was conducted on the use of Advantage and Heartgard. I was told that using these products together cause neurological disorders in your dog. Has anyone heard of this study or of it happening? I would like to know more about it since my puppy uses both of these together every month.
thanks

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All of my dogs (four German Shepherds) got/get FrontLine and Heartguard at the same time every month. They are Seeing Eye puppies and and the Seeing Eye has all their puppy raisers give the two meds together every month (over 600 dogs a year) and I have never heard of or experienced any neurological effects... Maybe Advantage is different chemically than FrontLine? Thats interesting...
 
Advantage and Frontline are two different drugs. I've never heard of either having any interactions with Heartgard, however. Presumably that is the way most people use it - a flea med in conjunction with heartworm preventative.

Where was this study published?
 
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I know that heart guard and interceptor are pretty much the same drug, and many of our clients give their animals advantage and interceptor at the same time. Our office has never seen any neurological disorders associated with the two drugs used together. I would be interested in knowing who published the study.
 
Dogtor said:
I recently heard a study was conducted on the use of Advantage and Heartgard. I was told that using these products together cause neurological disorders in your dog. Has anyone heard of this study or of it happening? I would like to know more about it since my puppy uses both of these together every month.
thanks

I have not heard this, and I recently took veterinary pharmacology and parasitology (last year). Advantage is "Imidacloprid" (vs. Frontline, which is Fipronil) and Heartgard is Ivermectin (Heartgard Plus has pyrantel as well).

According to the drug book (Plumb's), for Advantage: "The manufacturer states that the compound has been shown to be physically compatible with fenthion, lufenuron, milbemycin, praziquantel, pyrantel pamoate and febantel" (p.445). (So it is compatible with Program and part of the Heartgard Plus).

When I was a puppy raiser for Guide Dogs for the Blind, Inc. I used both Advantage and Heartgard together without a problem.
 
It is funny that two of you have mentioned being puppy raisers because I am currently a raiser myself. I did not see the article, I was told by a fellow raiser of this study. She was not sure about the article but it was in a popular dog magazine. I have been looking for the article but have not had success.
Thank you for all of your input.
 
Yeah puppy raisers! I love it! What do you raise and for which school? Like I said above, weve got shepherds for the Seeing Eye... Pasha, Truffles, Aster and Kirby... I love my girls 🙂
 
PAThbrd said:
Yeah puppy raisers! I love it! What do you raise and for which school? Like I said above, weve got shepherds for the Seeing Eye... Pasha, Truffles, Aster and Kirby... I love my girls 🙂
once you've gone,

I have my first puppy with Guide Dogs for the Blind. He is a yellow lab and is super massive for his age. Only 5 mo. and 65 lbs if not already over ( I weighed him 2 weeks ago). I am having so much fun and it does take a lot of time but it is well worth it. I am glad to hear from other raisers!
 
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