May 29, 2011
442
1
Status
Pre-Medical
pH = pKa + log [conjugate base/acid]

pH = 6.1 + log [1/10] , log of 0.1 = -1

pH = 6.1 + -1

pH = 5.1
 
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May 29, 2011
442
1
Status
Pre-Medical
Because you want to know the relationship between the +2 and +1 forms. So you start with the +2 version, which is with just the hydroxyl deprotonated, so the next proton to be lost comes from the NH in the ring, pKa 6.1. Going from the +2 to the +1 is entirely based upon that group losing or gaining a proton.
 
Feb 28, 2012
116
0
Status
Because you want to know the relationship between the +2 and +1 forms. So you start with the +2 version, which is with just the hydroxyl deprotonated, so the next proton to be lost comes from the NH in the ring, pKa 6.1. Going from the +2 to the +1 is entirely based upon that group losing or gaining a proton.
ahh got it. thanks!
 
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