• SDN Site Updates

    Hey everyone! The site will be down for approximately 2 hours on Thursday, August 5th for site updates.

  • How To ACE Your Medical School Interview

    In this webinar hosted by SDN with experts from BeMo Academic Consulting, you will learn a simple five-step process to help you translate your interview invitation into an acceptance.

johndoe3344

Full Member
10+ Year Member
Jun 1, 2009
432
6
Status (Visible)
  1. Resident [Any Field]
FA is being confusing... can someone let me know if I got this right?

High potency, typical: HIGH extrapyramidal, LOW anticholinergic, LOW other
Low potency, typical: LOW extrapyramidal, HIGH anticholinergic, HIGH other
Atypical: LOW extrapyramidal, LOW anticholinergic, HIGH other

Where by "other" I mean anti- alpha1, H1, serotonin side effects.
 

kaleerkalut

Full Member
Jan 5, 2011
491
3
Status (Visible)
  1. Medical Student
FA is being confusing... can someone let me know if I got this right?

High potency, typical: HIGH extrapyramidal, LOW anticholinergic, LOW other
Low potency, typical: LOW extrapyramidal, HIGH anticholinergic, HIGH other
Atypical: LOW extrapyramidal, LOW anticholinergic, HIGH other

Where by "other" I mean anti- alpha1, H1, serotonin side effects.

I believe this is correct. The only part I'm unsure about is the Atypical "LOW anticholinergic". Hopefully somebody else can chime in as well.
 

MrBeauregard

Soon-to-be PGY-1
10+ Year Member
7+ Year Member
Mar 10, 2009
619
45
Status (Visible)
  1. Medical Student
Yes, this is correct.

With the atypicals, instead of worrying about 5-HT2, alpha, dopamine or H1 effects, you need to worry about weight gain/diabetes with both Clozapine and Olanzapine. Clozapine obviously needs weekly checks for agranulocytosis. Ziprasidone can also cause QT prolongation.
 
This thread is more than 9 years old.

Your message may be considered spam for the following reasons:

  1. Your new thread title is very short, and likely is unhelpful.
  2. Your reply is very short and likely does not add anything to the thread.
  3. Your reply is very long and likely does not add anything to the thread.
  4. It is very likely that it does not need any further discussion and thus bumping it serves no purpose.
  5. Your message is mostly quotes or spoilers.
  6. Your reply has occurred very quickly after a previous reply and likely does not add anything to the thread.
  7. This thread is locked.