Any biochem pros/junkies can help me out?

[Necr0sis713]

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Hey guys,

In my cell bio class we have an extra credit assignment which is quite simple and straightforward. I asked my professor before the due date whether I got the answer right and he told me I was wrong, so I have until Monday to turn it in.

The question is: Where does the CO2 come from in the krebbs cycle OTHER THAN WATER. Also, my book says it's not from O2 taken in from respiration. I thought it was from the carboxyl groups on citrate, but he said it was wrong.

Any ideas?

 

[Cotterpin]

There are two steps here that yield CO2. Isocitrate --> alpha-Ketoglutarate and alpha-Ketoglutarate --> Succinyl-CoA.

Wait.... did I just help you with homework? Isn't that illegal on SDN?

 

[Necr0sis713]

I forgot to mention: I meant to ask where does the o in co2 in the Krebs cycle come from

 

[K9TestRun]

The first CO2 that is released via isocitrate dehydrogenase comes from the actetyl-CoA attached in the first step. The carbon does not come from citrate.

 

[NotASerialKiller]

There are two steps here that yield CO2. Isocitrate --> alpha-Ketoglutarate and alpha-Ketoglutarate --> Succinyl-CoA.

Wait.... did I just help you with homework? Isn't that illegal on SDN?

It'll be on your shoulders when this snowballs into a cheating IA in 2 years. Don't worry I'll remember to tag you in his sob-story thread.

 

[K9TestRun]

Track the position of the carbons throughout the cycle using the map @Cotterpin attached

 

[Cotterpin]

Where does the O in CO2 come from? I'm not sure I understand this question. Those are both decarboxylations, so they're all coming from carboxyl groups.

 

[K9TestRun]

There are two steps here that yield CO2. Isocitrate --> alpha-Ketoglutarate and alpha-Ketoglutarate --> Succinyl-CoA.

Wait.... did I just help you with homework? Isn't that illegal on SDN?

OP said the assignment already passed

 

[NotASerialKiller]

OP said the assignment already passed

In my cell bio class we have an extra credit assignment which is quite simple and straightforward. I asked my professor before the due date whether I got the answer right and he told me I was wrong, so I have until Monday to turn it in.

 

[Cotterpin]

OP said the assignment already passed

No, they have until Monday to turn it in.

 

[group_theory]

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