Raja,
Its very committed of you to want to attempt such a feat. However, consider the circumstances of appealing rejections at two schools (your top choices) that didn't grant you interviews. In other words, you may stir up something that could be a red flag next year if you re-apply to those schools, wanting them to remain as top choices. Politics play a part in everything in life, especially medical schools.
Channel your energy and fervor somewhere else and instead, make some calls or schedule meetings if you are close in proximity to the schools, to ascertain what exactly the school wants to see on your application next year in order that you might receive an interview. The interview is the deal-clincher. Its easy to look good on paper (most people can do it), but very few look as good or anything like their paper identity when it comes to the 3-dimensional meeting.
Of course, my advice would be a bit different if you had interviewed and felt a vibe that you had made a great connection, only to get rejected - then I would say take a stab at an appeal.
As far as most not getting into their top choices - that is directly related to most aiming at targets that are beyond their means! Be realistic and your chances for success are far greater. If you say you're gonna hit the 98% and you only hit 97% - you failed! But, if you were shooting for 96% and you hit 97% you exceeded your goal! 😎