Pharm was easier on Step 1 compared to Uworld.
Ethics was harder on Step 1 compared to Uworld.
Anatomy was about the same.
Biochemistry was about the same.
Neurology - I cannot comment because my exam had very few questions.
Microbiology was about the same.
Embryo - I cannot comment because my exam had very few questions.
Repro - I do not remember a single Repro question.
Renal was about the same.
Behavioral Science was about the same.
Respiratory was slightly easier on Step 1.
Other notes:
I found the questions to be longer on Step 1 compared to Uworld. Step 1 had way more laboratory results to go through, but my exam was also very Anemia focused. I was doing 46 questions in Uworld in 48 mins, and when I was taking Step 1 I was having trouble answering all of my questions in 60 mins. Be prepared to read a lot faster on Step 1 compared to Uworld.