In that five day period do they take into account other potential factors like aspirin, toradol/NSAIDs, fish oil, ect that may influence bleeding? I am sure you are fine with 5 days but I am overly cautious when it comes to neuraxial and thinners.
Is the case elective or urgent? If urgent , take into consideration the total picture and make your decision accordingly. They are guidelines, not rules.
The important finding of this study is the lack of statistical differences between the P2Y12 PRU values, per cent platelet inhibition, and PFA-ADP closure times in patients undergoing epidural steroid injections at 5 days compared with the values at 7 days after discontinuation of clopidogrel. These data support the 2010 published guidelines of the Scandinavian Society of Anaesthesiology and Intensive Care Medicine which suggest that 5 days of discontinuation of clopidogrel is adequate before a neuraxial block.8 The platelet inhibition as measured by the P2Y12 assay at day 5 after discontinuation showed inhibition of 29% or less, which is considered the level of a ‘semi-responder’.13 If minimal inhibition of platelet function is accepted before a neuraxial injection,15 similar to the recommendations of the different guidelines wherein patients on aspirin or non-steroidal anti-inflammatory agents or those with slightly elevated international normalized ratio values (1.4 or less) are acceptable for neuraxial injection,5–8 then values of 20% or less inhibition by the P2Y12 assay is probably acceptable for neuraxial blocks.