Asymptomatic HTN

Started by thegenius
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I think we do these people a disservice when we don't start antihypertensives. Most people can't see a PCP for an initial visit for at least six months.
which is why ACEP changed their recommendations from "accidentally overtreating is a real thing, so maybe think twice before starting new meds" to "just start them on something if they have nothing."

My (huge, flashing, and flaming) concern is that htn is not supposed to be diagnosable by the standard criteria on a single elevated measurement or on those who are sick/in pain for the most part. So we are really *still* running afoul of the concern ACEP had from 2013 until earlier this year - that we might be starting a daily medication for a temporary BP rise and leading to iatrogenic hypotension. But I do trust, especially after reading their reasoning on it, that starting meds is more benefit than harm for most people and assume we can use some common sense to feel out where the patterns for 'this is temporary' vs 'this is htn' exist.
 
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which is why ACEP changed their recommendations from "accidentally overtreating is a real thing, so maybe think twice before starting new meds" to "just start them on something if they have nothing."

My (huge, flashing, and flaming) concern is that htn is not supposed to be diagnosable by the standard criteria on a single elevated measurement or on those who are sick/in pain for the most part. So we are really *still* running afoul of the concern ACEP had from 2013 until earlier this year - that we might be starting a daily medication for a temporary BP rise and leading to iatrogenic hypertension. But I do trust, especially after reading their reasoning on it, that starting meds is more benefit than harm for most people and assume we can use some common sense to feel out where the patterns for 'this is temporary' vs 'this is htn' exist.

I'm not entirely opposed to starting or adjusting their meds. But for many of the reasons you write above I tend not to do it. It's a case-by-case basis and I suspect I do it less than the average ER doc. I certainly don't give an Rx for 6 months. That may not even be standard of care in the PCP office if you are starting someone on HTN medicine for the first time.

Just yesterday UC sent in an asymptomatic woman who was 200/100. They had the good sense to give clonidine 0.1 mg (should have been 0.2 mg) and wait like 30 minutes, and the BP went down to 185. After my history I restarted her two BP meds she has been on in the past that she stopped taking.
 
which is why ACEP changed their recommendations from "accidentally overtreating is a real thing, so maybe think twice before starting new meds" to "just start them on something if they have nothing."

My (huge, flashing, and flaming) concern is that htn is not supposed to be diagnosable by the standard criteria on a single elevated measurement or on those who are sick/in pain for the most part. So we are really *still* running afoul of the concern ACEP had from 2013 until earlier this year - that we might be starting a daily medication for a temporary BP rise and leading to iatrogenic hypotension. But I do trust, especially after reading their reasoning on it, that starting meds is more benefit than harm for most people and assume we can use some common sense to feel out where the patterns for 'this is temporary' vs 'this is htn' exist.
I usually prescribe, but tell them to take their BP at home or with a friend's machine. If it remains >140/90, then start the medication.
 
I usually prescribe, but tell them to take their BP at home or with a friend's machine. If it remains >140/90, then start the medication.
In the last year, I moved from an inner city, largely Haitian, community to a a suburban largely affluent community.

The adjustment has been rough. Going from blood pressure values that seem incompatible with nephron survival being their everyday functional status, to people checking their BP q15 minutes for 6 hours and wondering why they went from 131/65 (that's high for me, doc) to 175/66 with each check is an adjustment.

I wish I could prescribe the former new kidneys and the latter new brains.
 
I'm not entirely opposed to starting or adjusting their meds. But for many of the reasons you write above I tend not to do it. It's a case-by-case basis and I suspect I do it less than the average ER doc. I certainly don't give an Rx for 6 months. That may not even be standard of care in the PCP office if you are starting someone on HTN medicine for the first time.

Just yesterday UC sent in an asymptomatic woman who was 200/100. They had the good sense to give clonidine 0.1 mg (should have been 0.2 mg) and wait like 30 minutes, and the BP went down to 185. After my history I restarted her two BP meds she has been on in the past that she stopped taking.
“Good sense”. People need to stop giving clonidine to patients with hypertension. It’s essentially never appropriate and drives me up a wall when I see my anxiety, hypertensive patients on PRN clonidine. Its duration of action is ~4 hours and can potentially cause rebound hypertension.
 
“Good sense”. People need to stop giving clonidine to patients with hypertension. It’s essentially never appropriate and drives me up a wall when I see my anxiety, hypertensive patients on PRN clonidine. Its duration of action is ~4 hours and can potentially cause rebound hypertension.

I'm not sure I believe the four-hour duration of action. I take it for sleep. 0.3, and my muscles just "quit" and really won't work the next day at the gym. I learned not to do that if I want to lift.
 
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“Good sense”. People need to stop giving clonidine to patients with hypertension. It’s essentially never appropriate and drives me up a wall when I see my anxiety, hypertensive patients on PRN clonidine. Its duration of action is ~4 hours and can potentially cause rebound hypertension.
I thought the duration of action was much longer, like much, much longer. It gives a decent decrease in BP in that 4-Hour window but (unless I'm misremembering something) you actually measure toxicity and total exposure in how much you've taken over the last 36 hours because the half-life is just an eternity and seemingly appropriate amounts can lead to toxicity the next day if you repeatedly dose based on BP rather than "total amount ingested".
 
In the last year, I moved from an inner city, largely Haitian, community to a a suburban largely affluent community.

The adjustment has been rough. Going from blood pressure values that seem incompatible with nephron survival being their everyday functional status, to people checking their BP q15 minutes for 6 hours and wondering why they went from 131/65 (that's high for me, doc) to 175/66 with each check is an adjustment.

I wish I could prescribe the former new kidneys and the latter new brains.
I'm sure if the Apple Watch that is released next week has built-in BP monitoring, our number of asymptomatic hypertensive patients is going to increase.
 
“Good sense”. People need to stop giving clonidine to patients with hypertension. It’s essentially never appropriate and drives me up a wall when I see my anxiety, hypertensive patients on PRN clonidine. Its duration of action is ~4 hours and can potentially cause rebound hypertension.

Not a single one time dose. I think it's perfect for single use around the histrionics of elevated BPs.
I do think it's a terrible long term HTN med though.
 
Rebound hypertension is for 900mcg of clonidine and taking it for weeks and then abruptly taking it out.

Clonidine 0.1 is useful for getting the nurses and patients to calm down. It’s not a good long term medicine

I do give patients losartan-hctz if they want something I usually do two classes since in all honesty they will get therapeutic inertia in Trying to treat their bp
 
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I thought the duration of action was much longer, like much, much longer. It gives a decent decrease in BP in that 4-Hour window but (unless I'm misremembering something) you actually measure toxicity and total exposure in how much you've taken over the last 36 hours because the half-life is just an eternity and seemingly appropriate amounts can lead to toxicity the next day if you repeatedly dose based on BP rather than "total amount ingested".

Oral half life is 12-16 hours . I had to look it up because I took 0.2mg late yesterday to pass TFO after a plane trip home and now the "poisoned" status effect animation (like in a video game) is above my head all day today.
 
Not a single one time dose. I think it's perfect for single use around the histrionics of elevated BPs.
I do think it's a terrible long term HTN med though.

Rebound hypertension is for 900mcg of clonidine and taking it for weeks and then abruptly taking it out.

Clonidine 0.1 is useful for getting the nurses and patients to calm down. It’s not a good long term medicine

I do give patients losartan-hctz if they want something I usually do two classes since in all honesty they will get therapeutic inertia in Trying to treat their bp

Just going to sort of address both of you at once. You're probably right, but having seen what happens if you give too much clonidine (aka you need to admit the person for 1-2 days for hypotension resistant to IV fluids and most pressors) I just stay the hell away from it. I get a lot of patients in Miami who get a dose of it at their PCP or an urgent care center and then get sent to me. And I honestly never have seen anyone suffer overdose toxicity with that one dose, but in New York City it was not uncommon to have a PCP give 0.2 followed by 0.1 or even sometimes 0.2 twice and then send them over *nominally* for recalcitrant hypertension only for them to be rocking into the ER 87/42 because it's been 60 and 120 minutes since their dosing due to ambulance time.

Because of that I completely avoid clonidine for hypertension (I'll use it for opiate withdrawal, even though that's beginning to fall out of favor) unless the complaint is literally asymptomatic hypertension on a patient who's supposed to be taking clonidine but isn't and it's a holiday weekend so they can't go to the pharmacy anytime soon to pick up their home meds.

Oral half life is 12-16 hours . I had to look it up because I took 0.2mg late yesterday to pass TFO after a plane trip home and now the "poisoned" status effect animation (like in a video game) is above my head all day today.

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what does that mean?

"pass the **** out".

I got home after a long day of travel and my brain was doing that thing it does where it plays sound clips from video games that I remember from the early 90s, then thinks about friends I had in elementary school before we moved, then remembers about how I shouldn't have traded the "40/40 Club" Rickey Henderson card to the one friend only for him to not take care of it, followed by trying to remember what data I was supposed to get to my accountant next week who reminds me of the host of MTV's "Remote Control", then...


0.2mg Clonidine. Stop it, brain.
 
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US FDA clears Apple Watch hypertension feature

Looking forward to this...
Increased patient volume in the ER at 2 am... 😀