B-cell

[be successful]

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are the B - cells mature and differentiate in bone marrow or Immature B cells are produced in the bone marrow then migrate to secondary lymphoid tissues to complete differentiation ?

i searched about it and found differences so what do you think ?

 

[ManaPool]

B-cells mature in secondary lymphoid organs after waiting to be introduced to an APC, then factors make a fair amount of these convert to Plasma cells.

 

[be successful]

thank you ,,,,,, but still i read some books that say B cell mature in bone marrow !!!!

 

[ManaPool]

thank you ,,,,,, but still i read some books that say B cell mature in bone marrow !!!!

Ya and some glycolysis processes are activated even when Glucagon is ruling. Don't focus on trees.