USMLE B cells/humoral immunity in DiGeorge Syndrome

[Northerncardinal]

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what's the impact of thymic aplasia on humoral immunity?

 

[Phloston]

what's the impact of thymic aplasia on humoral immunity?

There's an NBME question on this, and they want you to know humoral/B cell function is completely normal in DiGeorge. In theory, yes, T cells activate B cells, but any B cell-related insufficiency that carries over humorally is significantly lesser compared to SCID, for instance.