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- May 13, 2016
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Colchicine most likely relieves gout symptoms through what mechanism?
A. Prevention of uric acid diffusion through cell membranes
B. Inhibition of leukocyte phagocytosis of uric acid crystals
C. Inhibition of uric acid formation
D. Maintenance of the pH optimum of PRPP synthetase
I thought the answer would be C. If phagocytosis is inhibited wouldn't the pain be worse?
Also what is the difference between synthase vs. synthetase vs. ligase?
A. Prevention of uric acid diffusion through cell membranes
B. Inhibition of leukocyte phagocytosis of uric acid crystals
C. Inhibition of uric acid formation
D. Maintenance of the pH optimum of PRPP synthetase
I thought the answer would be C. If phagocytosis is inhibited wouldn't the pain be worse?
Also what is the difference between synthase vs. synthetase vs. ligase?