Bio Question

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IzzyMarieDMD

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I can't find a good explanation for substrate-level phosphorylation and how it is different from oxidative phosphorylation. Can anyone explain?
 
IzzyMarieDMD said:
I can't find a good explanation for substrate-level phosphorylation and how it is different from oxidative phosphorylation. Can anyone explain?

first of all,SLP can occur under either anaerobic or aerobic conditions---you need oxygen for oxidative phosphorylation. SLP involves the transfer of a P group to ADP through some intermediate...it happens in glycolysis and krebs,while oxP happens during the final part of cellular respiration at the inner mito membrane. also,oxP involves electron carriers that reduce and oxidize carriers that produce ATP by pumping protons across a gradient.


slp=substrate level,oxp=oxidative
 
IzzyMarieDMD said:
I can't find a good explanation for substrate-level phosphorylation and how it is different from oxidative phosphorylation. Can anyone explain?

Just know that substrate level phosphorylation is associated with glycolysis and tca (and other metabolic pathways)... which take place in the cytosol and mitochondra respectively. adp is phosphorylated from a phosphate released from the reactant of the reaction to form ATP.

oxidative phosphorylation is a process rather than a step....and it is key in the electron transport chain in creating ATP from the energy released during the redox reactions. oxidative phosphorylation/electron transport take place in the inner mitochondrial membrane.

i'm guessing you didn't take biochem 2 with dr. logan? 🙂

jb!
 
jackbauer! said:
Just know that substrate level phosphorylation is associated with glycolysis and tca (and other metabolic pathways)... which take place in the cytosol and mitochondra respectively. adp is phosphorylated from a phosphate released from the reactant of the reaction to form ATP.

oxidative phosphorylation is a process rather than a step....and it is key in the electron transport chain in creating ATP from the energy released during the redox reactions. oxidative phosphorylation/electron transport take place in the inner mitochondrial membrane.

i'm guessing you didn't take biochem 2 with dr. logan? 🙂

jb!
nope no biochem yet, some of these questions make me wish I had though :scared:
 
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