BIO question

[sfoksn]

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What is a promoter site?

a. A start site for DNA replication
b. A start site for DNA transcription
c. the binding site for regulatory proteins that will allow for transcription.
d. the site on DNA at which RNA polymerase binds to initiate transcription.
e. More than one of these.


What do you guys think?

 

[wantVCUdental]

d

 

[sfoksn]

Hello VCU dental, why do you say that?

Don't transcription factors also bind to promoter region?

or does RNA polymerase bind to promoter first then the TF's bind to polymerase?

 

[wantVCUdental]

Hello VCU dental, why do you say that?

Don't transcription factors also bind to promoter region?

or does RNA polymerase bind to promoter first then the TF's bind to polymerase?

You are correct, however, transcription factors are not part of the answer 😛

In this question, choice d is the most suitable answer.

 

[azar87]

the promoter site contains the start Codon AUG i beleive to allow RNA polymerase bind and allow synthesis to proceed.

 

[ddsjc2014]

D here as well..

 

[sfoksn]

then where does the regulatory protein bind to?

do they mean enhancers and repressors by regulatory protein?

If so, then i guess they don't bind to promoter region 😛

 

[ddsjc2014]

I guess Regulatory Protein produces coenzymes, repressors for example and then that binds to the operator region between the promoter and coding region to control the activity of RNA Pol. And there is Regulatory Region such as TATA box just upstream of coding region where transcription factors bind and regulate transcription.
Correct me if I'm wrong.

 

[JBarr29]

the promoter site contains the start Codon AUG i beleive to allow RNA polymerase bind and allow synthesis to proceed.

Don't go by this - incorrect
The answer is more than one.
The promoter site is an upstream region of DNA where Transcription factors can bind to promote the transcription of genes or genes (if an operon).
The AUG start codon is used for translation which codes for a methionine usually, but has really nothing to do with trancription. Because the nascent transcripts are processed before translation, the sequence that codes for AUG in the DNA may be further downstream, not necessarily at the 5' end.

 

[JBarr29]

I guess Regulatory Protein produces coenzymes, repressors for example and then that binds to the operator region between the promoter and coding region to control the activity of RNA Pol. And there is Regulatory Region such as TATA box just upstream of coding region where transcription factors bind and regulate transcription.
Correct me if I'm wrong.

Thats a good answer, didnt read that one.

 

[kpanesar]

yeah don't get so confused with everythign all you need to know is....

operator - sequence of nontranscribable DNA that is the repressor binding site
promoter - sequence of nontranscribable DNA that is the initial binding site for RNA pol
regulator - codes for repressor molecules that bind to the operator to block RNA pol