Biochem question

[Eyegirl2k7]

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In the epithelium of the ciliary body, when B2 adrenergic stimulation activates cAMP through a Gs protein, is the Na/K atpase inhibited, causing a depolarization of the membrane?

Luv,
eyegirl

 

[cpw]

ewww pharm...

I remember Gs activates cAMP , but I'll look up the Na/K ATPase..

okay.. here it is directly off my flow chart from pharm.

Gs activates Adenylate cyclase -- which increases cAMP concentration -- which increases protein kinase activity --- which INCREASES channel phosphorylation -- which alters the properties of the ion channel -- which alters the charge distribution across the membrane.

hope this helps... good luck with pharm!!

 

[r_salis]

Dear cpw and eyegirl,

I am on vacation until next Monday. I have nothing to study because I'm between quarters, and frankly I can't even remember where my school is right now.

😀

(Feel free to mock me when you're on semester break and I'm in school. 🙂 )

 

[cpw]

Originally posted by r_salis
Dear cpw and eyegirl,

I am on vacation until next Monday. I have nothing to study because I'm between quarters, and frankly I can't even remember where my school is right now.

😀

(Feel free to mock me when you're on semester break and I'm in school. 🙂 )

well, i've already passed both semesters of pharm. I'm just trying to help her out. 😉 Thank god that class is over!!

I do have finals in a week though. And don't worry.. when you're back in class and I"m lying on the beach somewhere with the man.. I'll make sure you know about it, girl. 😎 😀 😉

 

[HighlyFanatic]

Originally posted by cpw
ewww pharm...

lol! pharm is good 😀 (ex-pharmacologist talking here)