Please don't tell me you were actually thinking of relying on public trans to get around buffalo?
The only good thing they have is the metro to go from UB to the sabres games.
Renting a car will make your life easier. Don't venture too far south of the school past winspear if you are unfamiliar with the area. You will start to see a lot of blinged out caddys and lincolns. Probably don't want to stop too long at the stop signs there during the day and not at all at night.
I am exaggerating a bit but enjoy your time there. 🙂