Slightly different take here from a PD. As above, yes, we rarely look closely at SoD transcripts unless there is something on the letter from the academic dean. Which again, we rarely look at in detail. But we all do look at how an applicant handles adversity. If you can present a good case about how you fell short and how you worked to overcome that deficiency. I am more impressed with that than a CBSE of 80+. Those applicants who do not face adversity in life have a tougher time in residency when adversity hits. And it will hit you, regardless of how smart you are or hard you work. This is how our selection committee works at my institution, we look very closely at where someone comes from, what adversity they have experienced and how they have succeeded.
As an example: In the recent past, we selected/ranked higher an applicant with slightly lower scores because this person was homeless in their teenage years and overcame that to become the first person in their family to go to college.