Ok here's the deal. I currently have a 89.34% in my lab class and if I'm able to argue these few points back I can get an A in the class. There was a case involving proper selection of an antimicrobial for empiric treatment of VAP in a relatively healthy (normal hepatic/renal function, hemodynamically stable) I don't have the case in front of me anymore so thats about all the detail I can remember. I selected cefepime 1g q12h but the teacher knocked it down a letter grade stating that this is less correct then a 2g q12h dose. If anyone wants to help me search and find some literature stating that the 1g q12h dose is adequate and the 2g q12h hasn't been shown to be superior for severe VAP I would greatly appreciate it! I already presented her with several sources showing the 1g q12h is an acceptable dosage, but I really need some literature showing the equivanlency in efficacy to the 2g dose.