I think changing out the femoral line within 3 hours of arrival to an ICU is crazy. The data to suggest that femoral line infectious complications is much higher than subclavian is weak at best, and I would use those first few hours to figure out how to best resuscitate the patient. There is a Cochrane review on CVC insertion site that demonstrated that LONG-TERM CVC insertion in the femoral site resulted in more thrombotic complications, and more "catheter related infections," aka the tip of the catheter grew out a microorganism, but this is not a patient orientated outcome. In terms of patients with frank sepsis from their lines there was no statistically significant difference between subclavian lines and femoral lines.
These complications frequently occur later in the patients course. That being said if the CVC was put in the femoral site in the emergency department the chances are it wasn't placed under optimal sterile conditions (otherwise why did they choose the femoral site?), and this type of line insertion was not assessed in the aforementioned literature and therefore my assumption is they have a higher infectious complication rate. Therefore I would change the line whenever it was most convenient for me and the nurses to a SC, of IJ line.
Also one common misconception is that the central line is a life saving intervention, similar to intubation/antibiotics. While central lines make ours and nurses lives easier and provide access for centrally administered drugs, there is no data to suggest that a CVC improves patient orientated outcomes.
Merrer et al. Complications of Femoral and Subclavian Venous Catheterization in Critically Ill Patients. JAMA. 2001;286(6):700-707.