Chemical burns can be blinding. Many cleaners contain base, and it can be a serious problem. Refer to this tutorial about ocular trauma:
http://webeye.ophth.uiowa.edu/eyeforum/trauma.htm
CHEMICAL BURNS: POST-IRRIGATION CARE
Base injuries are more worrisome as they can penetrate deeper into ocular tissue. Grading of corneal burns is based on extent of limbal ischemia, which indicates loss of corneal epithelial stem cells, and degree of corneal haze obscurring iris details.
Hughes Classification of Ocular Burns
Grade 1 (Very good prognosis)
No corneal opacity nor limbal ischemia.
Grade 2 (Good prognosis)
Corneal haze but iris details are clear. Less than 1/3 cornea limbus ischemia.
Grade 3 (Guarded prognosis)
Sufficient corneal haze to obscure iris details. 1/3 to 1/2 of cornea limbus ischemia.
Grade 4 (Poor prognosis)
Opaque cornea without view of iris or pupil. More than 1/2 of cornea limbus ischemia.
For chemical burns, injury grade is based on exam before irrigation has begun (it is rare that you will see patients before irrigation is initiated). Start irrigation IMMEDIATELY with Normal Saline or Lactate Ringers Solution (2 liters)wait 5 min and check pH. Additional irrigation as needed until pH is 7.0-7.5. Continue irrigation until pH is normalcompare pH to the other eye because some pH paper will always read either too alkaline or acidic. Sweep for particulate matter and examine fornices. Check IOP. Call the senior resident. Note limbal ischemia, epithelial defect, stromal loss/haze, edema, AC depth, inflammation, and lens clouding.
MANAGEMENT OF CHEMICAL BURNS
Grading helps to determine the aggressiveness and course of treatment. Treatment modalities include some or all of the following depending on the severity of the burn:
Debride necrotic tissue
Bandage contact lens
Quinolone: 1 gtt 4-6x/day (prevents infection)
Prednisolone phosphate: 1 gtt q 1-2 hr while awake (reduces inflammation)
Vitamin C: 1-2 gm po QD (reduces corneal thinning/ulceration)
10% sodium citrate: 1 gtt q 2 hr while awake (chelates Ca++ and impairs PMN chemotaxis)
Scopolamine 0.25%: 1 gtt TID (reduces pain/scarring with AC inflammation)
10% Mucomyst (n-acetyl-cysteine): 1 gtt 6x/day (mucolytic agent and collagenase inhibitor)
Doxycycline 100 mg po bid (collagenase inhibitor)
Glaucoma gtts/oral diamox if IOP elevated
Significant injury may require admission