Clinical Use of Estrogen

Discussion in 'Step I' started by MudPhud20XX, 05.18.14.

  1. SDN is made possible through member donations, sponsorships, and our volunteers. Learn about SDN's nonprofit mission.
  1. MudPhud20XX

    MudPhud20XX 2+ Year Member

    Joined:
    11.25.13
    Messages:
    1,134
    Status:
    Medical Student
    One of them is osteoporosis prophylaxis right? But doesn't estrogen stimulate both osteoblast and osteoclast? Can anyone explain this? Many thanks in advance.
     
  2. SDN Members don't see this ad. About the ads.
  3. bulldogmed

    bulldogmed 2+ Year Member

    Joined:
    03.07.12
    Messages:
    226
    Status:
    Resident [Any Field]
    The way I understand it is that the human body constantly has bone resorption and building going on. That's part of bone physio. In women, part of that is due to estrogen production which stimulates both arms of that process. In osteoporosis, you're taking away some of the stimulus for bone production, ultimately leading to bone loss. HRT attempts to correct this, though there are cardiovascular side effects that may lead to contraindications. Importantly for boards though, all lab values in osteoporosis are normal. Hope this helps.
     
    BlueArc and MudPhud20XX like this.

About the ads

Share This Page