Close Margin<1mm- LE Sarcoma -Low Grade- Myxofibromsarcoma

[johnthomas75]

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I'm trying to estimate the recurrence risk for this patient both with and without radiation.

Ive compiled a list of papers that look at the effect of a close margin (<1mm) on recurrence risk but nothing that has quantified that risk based on grade.

Any good references out there?

johnthomas75
http://the-d-o-c-t-o-r.blogspot.com/

 

[Pointless]

My guess is that there is nothing in the literature to quantify risk for something that specific. Where is the close margin? Why not re-excise?

 

[napoleondynamite]

NCCN recommends RT in low grade if margins <1cm. In the Yang/NCI trial, RT improved LC even in low grade.

Agree would re-x in this case. If impossible, would do RT.

 

[deleted4401]

Planned close margin or unplanned? Sarcoma literature has difference in outcome and recurrence rates with a planned close margin are fairly low. Let me see if I can find the data.

 

[HatchetJack]

This may be the paper that Simul is referring to

http://www.ncbi.nlm.nih.gov/pubmed/20056340

 

[deleted4401]

This guy: http://www.ncbi.nlm.nih.gov/pubmed/11764430