Confused on spleen microanatomy

[anvp]

---

Members don't see this ad.

I used a marker for CD206/manose receptor and this is how it looks in the human spleen. What do you think is actually labeling? My guess is the sinusoids…

It should be labeling 206+ macrophages…

 

[tiredguy]

Are they littoral cells, maybe?

 

[mike-sheree]

Perhaps marginal zone macrophages surrounding white pulp and the background dark areas are the red pulp?