Confused on spleen microanatomy

[anvp]

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I used a marker for CD206/manose receptor and this is how it looks in the human spleen. What do you think is actually labeling? My guess is the sinusoids…

It should be labeling 206+ macrophages…

 

[tiredguy]

Are they littoral cells, maybe?

 

[mike-sheree]

Perhaps marginal zone macrophages surrounding white pulp and the background dark areas are the red pulp?