Step I Conn's Syndrome

[Kluver_Bucy]

What is the mechanism of increased serum bicarbonate in Conn's? Thanks for your help.

 

[idq1i]

Increased Na absorbtion leads to lumen negativity, resulting in greater acid secretion, leading to a metabolic alkalosis.

Also: High aldo leads to low K, which results in the release of ic K at the expense of H+