Hey Psu , i will tell you the way I remember it:
1) First and foremost, the normal human physiology will always try to be on a state of equilibrium. The body knows a hormone like glucagon will increase blood glucose , so taking advantage its secreted near beta cells , glucagon takes the opportunity to promote insulin secretion and therefore counterbalance its own actions. You can derive glucagon like peptide regulation from this also.
2) All the actions of insulin are to remove glucose from blood. How does it accomplishes that. Easy, by promoting uptake AND removing all sources for potential glucose , among them are obviously the aminoacids (aa) . So it tells blood aminoacids to go and become muscle instead of being around on the blood. By remembering this easy principle , you can remember that if blood aa´s are high, the body has created a mechanism so those same aas , activate insulin , and tells them to go to muscle (so they cant be captured by liver and become glucose)
3) GIP is just a "messenger" (not to be confused with 2nd messengers). When the duodenum /jejunum has SENSED LOCALLY high aas, fatty acids, glucose , sends its messenger GIP , so it can tell sleepy insulin to move out , and do its job.
Well thats the way I remember it , I hope I had helped and not confuse you more.
Feel free to ask anything , If its upon my knowledge´s grasp , i will be glad to help you,
Regards
Eduro
