Cytokines on Step 1

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Bojack Horseman

hey!
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Do you have to memorize all of the immunologic cytokines for step 1?..
I'm not sure how many I need to know for class, but there sure are a lot.

Interleukins, interferons, chemoattractants, complements, etc..... All with lovely, overlapping functions.😴

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There are some high-yield ones that are probably good to know (take what I say with a grain of salt; I'm still an M2). Like IL-1, IL-2, IL-4, IL-5, IL-8, IL-10, TNF, and TGF-beta. It helps me to organize them as proinflammatory (ex. IL-1, TNF, etc) vs. anti-inflammatory (the main ones being IL-10 and TGF-beta). Then, there are class switchers and chemoattractants (ex. IL-4, IL-5, IL-8). And so on.

Are you an M1? Just wondering, because between M1 year immuno and path so far in M2 year, I feel like the different cytokines and their functions have popped up enough times for me to have a pretty good idea of what the major functions of the ones I've listed are. If you're still an M1, I wouldn't sweat it too much since these will come up again and again a decent bit. Otherwise, unfortunately, it's just brute memorization. =/
 
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There are some high-yield ones that are probably good to know (take what I say with a grain of salt; I'm still an M2). Like IL-1, IL-2, IL-4, IL-5, IL-8, IL-10, TNF, and TGF-beta. It helps me to organize them as proinflammatory (ex. IL-1, TNF, etc) vs. anti-inflammatory (the main ones being IL-10 and TGF-beta). Then, there are class switchers and chemoattractants (ex. IL-4, IL-5, IL-8). And so on.

Are you an M1? Just wondering, because between M1 year immuno and path so far in M2 year, I feel like the different cytokines and their functions have popped up enough times for me to have a pretty good idea of what the major functions of the ones I've listed are. If you're still an M1, I wouldn't sweat it too much since these will come up again and again a decent bit. Otherwise, unfortunately, it's just brute memorization. =/

Thanks for the tips.

Yeah I am an M1. We are doing an immuno/micro block with basic pathology concepts strewn in with it all. Hopefully the repetition will help over time.
 
Wow. It's things like this that remind me how lucky I am to be a 4th year.

It gets better.
 
There are some high-yield ones that are probably good to know (take what I say with a grain of salt; I'm still an M2). Like IL-1, IL-2, IL-4, IL-5, IL-8, IL-10, TNF, and TGF-beta. It helps me to organize them as proinflammatory (ex. IL-1, TNF, etc) vs. anti-inflammatory (the main ones being IL-10 and TGF-beta). Then, there are class switchers and chemoattractants (ex. IL-4, IL-5, IL-8). And so on.

Are you an M1? Just wondering, because between M1 year immuno and path so far in M2 year, I feel like the different cytokines and their functions have popped up enough times for me to have a pretty good idea of what the major functions of the ones I've listed are. If you're still an M1, I wouldn't sweat it too much since these will come up again and again a decent bit. Otherwise, unfortunately, it's just brute memorization. =/

IL-6 is another good one to know along with the interferons (alpha and gamma more so than beta).

(sent from my phone)
 
and CCR5, CXCR4 (for HIV)

g9pepl.jpg
 
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