Oh, Virginia - so then forget what I said about conditions being comparable! Do you have any experience driving in the snow? First, the road crews do know how to handle it and will have everything in good condition shortly after the snow stops falling. But if you've never dealt with (real) winter conditions, here are a few quick tips:
Like I said before, watch the weather reports and avoid driving in a storm if you can help it. If conditions get bad, get off the roads and wait out the weather in a parking lot.
If there's snow on the road while you're driving, do everything more slowly than you think you need to. That means drive at a slower speed, don't brake hard, don't accelerate quickly, and don't swerve suddenly. (Drive like there's a full glass of water in the seat next to you that you don't want to spill.) The snow means you've got less traction to work with, and you don't want your wheels' static friction to switch to kinetic!
The good news is that you can go from Boston all the way to Hanover on interstates (93 -> 89 -> 91), so you won't have to deal with any winding mountain roads.
