DAT Question of the Day
Consider the process shown (pyruvate → acetyl-CoA).
Question:
What vitamin is most involved?
a) Vitamin C
b) Vitamin D
c) Vitamin B
d) Vitamin K
e) Vitamin A
Correct answer: c) Vitamin B (specifically Vitamin B1, thiamine)
Why? This reaction involves a decarboxylation step. Anytime you see oxidative decarboxylation of an alpha-ketoacid (such as pyruvate), thiamine (B1) should immediately come to mind.
For the DAT and OAT, cut through the noise:
• B1 is required for decarboxylation reactions
• It functions as a catalyst in energy production
• It is involved in the decarboxylation of alpha-ketoacids and branched-chain amino acids
This is exactly the level of thinking the exams expect.
The 2026 DAT Destroyer is now available, with many newly added Biology and Biochemistry questions written to reflect current DAT and OAT testing trends.
Official resources and classes:
DAT Destroyer – #1 DAT & OAT Test Prep by Dr. Jim Romano
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Free Facebook Study Group (includes Dr. Romano’s Biology Review):
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Official YouTube channel with DAT and OAT problem walkthroughs:
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