Bianca Cinquemani conducted an analysis of the below molecule . Which carbon has the functionality with the lowest pKa ?
a) 1
b) 2
c) 3
d) 4
e) 5
f) 6
Answer: C is correct.
Concept: The lowest pKa means the most acidic proton. We examine anion stability. By removal of the H as shown below, we obtain the most resonance forms, which stabilizes the anion.
a) 1
b) 2
c) 3
d) 4
e) 5
f) 6
Answer: C is correct.
Concept: The lowest pKa means the most acidic proton. We examine anion stability. By removal of the H as shown below, we obtain the most resonance forms, which stabilizes the anion.