ShySpliceosome Microbe lover 10+ Year Member Sep 5, 2013 #1 Advertisement - Members don't see this ad Why is a carboxylic acid a stronger deactivator (i.e. more electron-withdrawing) than an ester?
Advertisement - Members don't see this ad Why is a carboxylic acid a stronger deactivator (i.e. more electron-withdrawing) than an ester?
A ashtonjam Full Member 10+ Year Member Sep 5, 2013 #2 Esters will have an alkyl group on the oxygen that is electron donating. Carboxylic acids only have a proton there which doesn't add anything in terms of electron density. Upvote 0 Downvote
Esters will have an alkyl group on the oxygen that is electron donating. Carboxylic acids only have a proton there which doesn't add anything in terms of electron density.
