Personally I'd go for either Hofstra or Stony Brook, but like the others said it depends on which factors you consider more important. As for location, Upstate would be my last choice. Bing is in the middle of nowhere and all my friends who go there for undergrad say that the location definitely isn't their favorite thing about it. Of the four, Downstate is known for having the best clinical exposure if that's important to you (makes sense, being the only one in a major city). I couldn't really differentiate much between the other two because I'm just kinda pulling this stuff from the top of my head, so you'd have to do some research. Stony Brook is well-established but I've heard great things about Hofstra in its first few years. Best of luck!!