Disclaimer: These questions might seem elementary, sorry in advance.
In FC:
*DNA Pol α: acts as a RNA primase, elongates the primer w/ 20 DNA nucleotides, after which DNA Pol δ takes over
*DNA Pol δ: analogous to DNA Pol III, also w/ 3→5 exonuclease proofreading
^I was under the impression that DNA pol delta was used for the lagging strand whereas DNA pol epsilon is used for the leading strand. Is there a reason that DNA pol epsilon isn't mentioned?
*Telomerase: enzyme that has an intrinsic RNA primer and synthesizes DNA upstream of the 5 end → no shortening of chromosomes during replication
^I was under the impression that telomerase adds to the 3' end of the parental strand. Can someone comment on this?
Thank You.
In FC:
*DNA Pol α: acts as a RNA primase, elongates the primer w/ 20 DNA nucleotides, after which DNA Pol δ takes over
*DNA Pol δ: analogous to DNA Pol III, also w/ 3→5 exonuclease proofreading
^I was under the impression that DNA pol delta was used for the lagging strand whereas DNA pol epsilon is used for the leading strand. Is there a reason that DNA pol epsilon isn't mentioned?
*Telomerase: enzyme that has an intrinsic RNA primer and synthesizes DNA upstream of the 5 end → no shortening of chromosomes during replication
^I was under the impression that telomerase adds to the 3' end of the parental strand. Can someone comment on this?
Thank You.