Most programs will consider DO applications. Even some of the top programs will take 1-2 DO's per year if they have strong enough numbers, such as Brigham and Women's, Penn, Hopkins, Columbia, U. Washington, Yale, Wake Forest, & Barnes Jewish.
Other top programs will not take DO's under any circumstances, such as the top Cali programs (Stanford, UCSF, UCSD, UCLA), Duke, Mass General, and Cornell (although Cornell will take Carribean graduates).
I don't know much about the top midwest programs (Michigan, Mayo Clinic), but maybe someone else can elaborate on those.
peace...