Not really. Remember once your transcript is submitted in the fall, programs don't see what else you take.
Here's what you should take in fourth year, in order of importance:
1) Enough in-field rotations (and your AI) to get all your letters in order, through ERAS deadline
2) Really easy stuff you don't have to show up to in October-December so you can go on interviews. Ideally online or independent study or whatever. Can't stress that enough. You don't ever want to have to decline an interview because of a rotation.
3) January until graduation: whatever you feel like.
(plus fit taking Step 2 in somewhere)
For me, that was 4 weeks of light rotations so I could study for CK, 10 weeks of in-field (and related) rotations into early October, then 10 weeks of stuff I barely had to show up to for interviews. Then, I finished with 4 weeks of lighter stuff related to my field, 4 weeks of EM (which everyone should take at some point), and ended with all my vacation time I had saved.